Ozone therapy, free of side effects (as it is a non-protein molecule, eliminating the possibility of allergies or toxicity), can be administered to humans exploiting important therapeutic effects such as powerful bactericidal, fungicidal, and virus inactivation properties, obtained by the oxidation of microorganisms.

Ozone was discovered in the 1800s by Schónbein, a chemist born near Stuttgart, who during his experiments with electrolysis using oxygen mixtures, randomly smelled an unknown gas, which turned out to be ozone.
This discovery was later described in an article written by him in 1832, describing it as a pungent, acrid-smelling gas and defining it as "ozonized oxygen."
Today, studies on the use of ozone are beneficial. They have been carried out by the Universities of Siena and Padua and sent to the Ministry of Health, showing good clinical results in terms of reliability and tolerability.
Ozone therapy processes
Ozone oxygen therapy is divided into two different processes, performed at different times, depending on clinical indications: Small Ozonated Autohemotherapy (PAET) and Large Ozonated Autohemotherapy (GAET).
Main indications for ozone therapy
The main indications for oxygen-ozone therapy are: angiology and phlebology; internal medicine; neurology; dermatology; orthopedics and rheumatology; gynecology; immunology.
In general, there are no side effects associated with ozone oxygen therapy: those that may occur are related to the blood extraction itself, transfusion, and reinfusion (skin rashes, feeling of heat in the face, tachycardia). Ozone does not create toxic effects, and the molecule is completely free of allergenicity. Side effects related to blood reinfusion can be easily prevented by administering the blood slowly with ozone.