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Trigeminal neuralgia: Prognosis of prescribed drugs

Neuralgia


Trigeminal neuralgia is a nerve disorder that causes shooting or electric shock-like pain in parts of the face.
neuralgia-trigemino-medicines-indicated

It is a form of neuropathic pain, along with other conditions such as painful diabetic neuropathy or postherpetic neuralgia.

Neuropathic pain (NP) is defined as a disorder of the sensorimotor system and is distinctly different from nociceptive pain, which is a consequence of trauma, injury, or inflammation. The main difference between neuropathic and nociceptive pain is the absence of continuous nociceptive input in neuropathic pain.

Current medications for treating trigeminal neuralgia

The main classes of drugs used to treat trigeminal neuralgia include anticonvulsants, antidepressants, opioids, and topical treatments. However, despite the availability of multiple pain medication only 50% of patients respond to any given drug and there are numerous side effects. associated particularly with systemically administered drugs, which reduce their tolerability.

Similar to the rest of the world markets, this market will be predominantly driven by the increasing incidence of neuropathic pain as a result of the growing elderly population.which is most pronounced in Japan. However, unlike in other 7MM countries, most of the growth in the neuropathic pain market in Japan will be the result of the delayed implementation and continued growth of the Lyrica and the Cymbalta. Both drugs were launched in Japan approximately five years after their launch in the US and the EU. Moreover, both drugs are subject to extended exclusivity in Japan, with Lyrica's patent not due to expire in Japan until 2022, and Cymbalta's post-marketing exclusivity is estimated to extend to 2017.

 

Mariano Bueno

Dr. Mariano Bueno and his team

2 thoughts on “La neuralgia del trigemino: Pronóstico de los medicamentos indicados”

  1. I have suffered from trigeminal pain for about 10 years and I have taken lirica but tregretol makes me better, you have to take medication for oxygenation as these pains are terrible shocks that bring tears to your eyes. I have also been told that botox is good. In synthesis I am in crisis and although there are times when I am well suddenly it is activated, This is emotional or is it contributes the stress. Thank you very much for listening to me

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